Effect of Time Lapse on the Diagnostic Accuracy of Cone Beam Computed Tomography for Detection of Vertical Root Fractures

Abstract Accurate and early diagnosis of vertical root fractures (VRFs) is imperative to prevent extensive bone loss and unnecessary endodontic and prosthodontic treatments. The aim of this study was to assess the effect of time lapse on the diagnostic accuracy of cone beam computed tomography (CBCT) for VRFs in endodontically treated dog's teeth. Forty-eight incisors and premolars of three adult male dogs underwent root canal therapy. The teeth were assigned to two groups: VRFs were artificially induced in the first group (n=24) while the teeth in the second group remained intact (n=24). The CBCT scans were obtained by NewTom 3G unit immediately after inducing VRFs and after one, two, three, four, eight, 12 and 16 weeks. Three oral and maxillofacial radiologists blinded to the date of radiographs assessed the presence/absence of VRFs on CBCT scans. The sensitivity, specificity and accuracy values were calculated and data were analyzed using SPSS v.16 software and ANOVA. The total accuracy of detection of VRFs immediately after surgery, one, two, three, four, eight, 12 and 16 weeks was 67.3%, 68.7%, 66.6%, 64.6%, 64.5%, 69.4%, 68.7%, 68% respectively. The effect of time lapse on detection of VRFs was not significant (p>0.05). Overall sensitivity, specificity and accuracy of CBCT for detection of VRFs were 74.3%, 62.2%, 67.2% respectively. Cone beam computed tomography is a valuable tool for detection of VRFs. Time lapse (four months) had no effect on detection of VRFs on CBCT scans.

Resumo Um diagnostico correto e a tempo das fraturas radiculares verticais (FRVs) é essencial para prevenir extensa perda óssea, tratamentos endodônticos e próteses desnecessárias. O objetivo do presente estudo foi avaliar o efeito do tempo decorrido sobre a acurácia diagnóstica da tomografia computadorizada de feixe cônico (TCFC) para detecção de FRVs em dentes de cães tratados endodonticamente. Quarenta e oito dentes incisivos e premolares obtidos de três cães machos adultos tiveram os seus canais tratados. Os dentes foram divididos em dois grupos: no primeiro grupo (n=24) foram artificialmente induzidas FRVs, enquanto no segundo grupo (n=24) os dentes permaneceram intactos. As imagens de TCFC foram obtidas pela unidade NewTom 3G imediatamente após a cirurgia de indução das FRVs e uma, duas, três, quarto, oito, 12 e 16 semanas depois. Três radiologistas cegos para as datas das imagens avaliaram a presença/ausência de FRVs nas imagens de TCFC. Foram calculados os valores da sensibilidade, especificidade e acurácia, sendo os dados analisados por ANOVA e pelo programa SPSS v.16. As acurácias totais de detecção das FRVs imediatamente após sua indução e uma, duas, três, quarto, oito, 12 e 16 semanas depois foram respectivamente de 67,3%, 68,7%, 66,6%, 64,6%, 64,5%, 69,4%, 68,7% e 68%. O efeito do tempo decorrido foi sem significado estatístico (p>0,05). A TCFC produziu valores gerais de sensibilidade, especificidade e acurácia de 74,3%, 62,2% e 67.2%, respectivamente. A tomografia computadorizada de feixe cônico é uma ferramenta valiosa para detecção de FRVs. O tempo decorrido (quatro meses) não teve influência sobre a detecção de FRVs nas imagens de TCFC.

Hydatidiform mole: a statistical survey in west of Iran

Objective: To determine the incidence of hydatidiform mole in west of Iran

Methodology: This study was carried out on pregnant women referring for delivery in Hamadan province in west of Iran. We retrospectively evaluated medical records of all referring subjects to medical centers in Hamadan province between 1997 and 2006. All pregnant women referred to 11 referral hospitals as well as obstetric care facility centers in the province were studied. We recorded all cases with hydatidiform mole. Data Processing and statistical analysis were performed using SPSS version 16.0

Results: The incidence of hydatidiform mole in Hamadan province estimated 3.34 per 1000 pregnancies Between 1997 and 2006. It means 1 per 298.2 pregnancies had hydatidiform mole. The incidence rate of hydatidiform mole was considerably higher compared to reported from Japan, Turkey, Europe, USA, UK, China, Malaysia, whereas was lower than reported from Indonesia and India. The risk of recurrence rate of mole was higher than that reported in the UK, but lower than that shown in South Africa

Conclusion: The incidence of hydatidiform mole in Hamadan province of Iran seems to be high. Therefore early and rapid diagnosis of gestational tropho-blastic diseases in this region is strongly recommended